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HelpTest Code C2 Complement Component 2
Clinical Indications
Follow-up test for complement activity screening when CH50 is low or absent and AH50 is normal and high suspicion remains for complement deficiency.
Additional Test Codes
Epic Order Name: C2 COMPLEMENT 2
Sunquest Order Code: C2
Epic Px Code: LAB2111
Specimen Collection Type
Preferred: Gold
Acceptable: Red
Minimum Collection Volume
0.75 mL
Reference Range
1.6-4.0 mg/dL
Critical Value
n/a
Interpretation
Decreased C2 levels may be associated with increased susceptibility to infection (especially pneumococcal infections), systemic lupus erythematosus-like disease, rashes, arthritis, nephritis, and with C1-Esterase deficiency. Increased C2 levels are associated with the acute phase response.
Rejection Criteria
Non-frozen specimens. Specimens exposed to repeated freeze/thaw cycles. Specimens left to clot at refrigerated temperature.
Specimen Availability for Add-on Testing
This test cannot be added on (Critical Frozen!)
Specimen Stability
Frozen (preferred): 2 weeks
Ambient: 2 hours
Refrigerated: Unacceptable
Day(s) Performed
Monday and Thursday
Performing Lab - Department
TUKHS-BH-Mail Outs
CPT Code
86160
LOINC Code
4484-2
Test Alias
C2
C2 Antigen
C2 Level
Classical Pathway – Complement
complement classical pathway
Second component of complement