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Test Code COXB Coxsackie B Virus Antibodies

Clinical Indications

Detect neutralizing antibodies to coxsackie B virus.

Additional Test Codes

Epic Order Name: COXSACKIE B 1-6 (aka COXB)
Sunquest Order Code: COXB
Epic Px Code: LAB2167

Specimen Collection Type

Gold-top serum (preferred)
Red-top serum
CSF

Minimum Collection Volume

0.75 mL (blood)
0.3 mL (CSF)

Reference Range

Coxsackie B1: Less than 1:10
Coxsackie B2: Less than 1:10
Coxsackie B3: Less than 1:10
Coxsackie B4: Less than 1:10
Coxsackie B5: Less than 1:10
Coxsackie B6: Less than 1:10

Critical Value

N/A

Interpretation

Single positive antibody titers of greater than or equal to 1:80 may indicate past or current infection. Seroconversion or an at least fourfold increase in titers between acute and convalescent sera is considered strong evidence of current or recent infection.

Rejection Criteria

Contaminated, hemolyzed, or severely lipemic specimens

Specimen Availability for Add-on Testing

2 days

Specimen Stability

Refrigerated (preferred): 2 weeks
Ambient: 48 hours
Frozen: 1 year

Day(s) Performed

Mon-Fri

Performing Lab - Department

TUKHS-BH-Mail Outs

CPT Code

86658 × 6

LOINC Code

N/A

Test Alias

Coxsackie Antibody, Neutralization
Coxsackie B
Coxsackie B Antibody Panel-Serum
Coxsackie B virus antibody profile, IgG, IgM
Enterovirus

Additional Information / Notes

Parallel testing is preferred and convalescent samples must be received within 30 days from receipt of acute samples. Mark samples plainly as “acute” or “convalescent.”

Note: The clinical significance and criteria for interpretation of results from CSF have not been established.