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Test Code DSS2 Drug Screen 9 Panel, Serum or Plasma - Immunoassay Screen with Reflex to Mass Spectrometry Confirmation/Quantitation

Important Note

This test should only be ordered on transplant patients who are unable to make urine.  Otherwise, our in-house Urine Drug Screen (UDS) should be ordered.

Clinical Indications

Monitor patient compliance.

Additional Test Codes

Epic Order Name:
Sunquest Order Code: DSS2
Epic Px Code: LAB

Specimen Collection Type

Gray-top (sodium fluoride/potassium oxalate) plasma (preferred)
Also acceptable: Red-top (no additive) serum, or green-top (sodium heparin), lavender-top (EDTA), or pink-top (K2EDTA) plasma

Minimum Collection Volume

8.0 mL

Reference Range

Drugs Covered and Cutoff Concentrations

Drugs/Drug Classes

Screen

Amphetamines

30 ng/mL

Methamphetamine

30 ng/mL

Barbiturates

75 ng/mL

Benzodiazepines

75 ng/mL

Buprenorphine

Effective Aug 15, 2016
1 ng/mL

Cannabinoids

30 ng/mL

Cocaine

30 ng/mL

Methadone

40 ng/mL

Opiates

30 ng/mL

Oxycodone

30 ng/mL

Phencyclidine

15 ng/mL

Critical Value

N/A

Interpretation

Drugs/Drug classes reported as “Positive” are automatically reflexed to mass spectrometry confirmation/quantitation. An unconfirmed positive immunoassay screen result may be useful for medical purposes but does not meet forensic standards. The absence of expected drug(s) and/or drug metabolite(s) may indicate non-compliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, or limitations of testing. The concentration at which the screening test can detect a drug or metabolite varies within a drug class. Specimens for which drugs or drug classes are detected by the screen are automatically reflexed to a second, more specific technology (GC/MS and/or LC-MS/MS). The concentration value must be greater than or equal to the cutoff to be reported as positive. Interpretive questions should be directed to the laboratory.

For medical purposes only; not valid for forensic use.

Rejection Criteria

Specimens exposed to repeated freeze/thaw cycles. Separator (gel) tubes. Plasma or whole blood collected in light blue-top (sodium citrate) tube.

Specimen Availability for Add-on Testing

Due to the substantial specimen volume required for this test (absolute minimum of 3 mL serum or plasma), and the fact that the serum or plasma must be removed from the cells within 2 hours of collection, this test generally cannot be added on.

Specimen Stability

Refrigerated (preferred): 2 weeks
Ambient: 1 week
Frozen: 3 years

Day(s) Performed

Sun-Sat

Performing Lab - Department

TUKHS-BH-Mail Outs

CPT Code

80307; if reflexed, add 80324; 80345; 80346; 80348; 80349; 80353; 80358; 80359; 80361; 80365; 83992 (Reflexed Alt Code: G0480)

LOINC Code

N/A

Test Alias

N/A

Additional Information / Notes

Screen-positive specimens are automatically confirmed by GC/MS and/or LC-MS/MS; additional charges may apply.

Cocaine and cocaethylene are more stable in fluoride-preserved plasma than serum.