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Test Code FCALP Calprotectin, Fecal

Clinical Indications

Aid in differentiation of inflammatory bowel disease (IBD) from irritable bowel syndrome (IBS) and other functional disorders of the gastrointestinal (GI) system. Aid in monitoring IBD and prediction of relapse.

Additional Test Codes

Epic Order Name: CALPROTECTIN, FECAL (aka FCALP)
Sunquest Order Code: FCALP
Epic Px Code: LAB10095

Specimen Collection Type

Random stool

Minimum Collection Volume

1 gram

Reference Range

50 µg/g or less: Normal
51-120 µg/g: Borderline elevated, test should be re-evaluated in 4-6 weeks.
121 µg/g or greater: Abnormal

Critical Value

n/a

Interpretation

N/A

Rejection Criteria

Specimens in media or preservatives.

Specimen Availability for Add-on Testing

2 Days

Specimen Stability

Refrigerated (preferred): 11 days
Ambient: 11 days
Frozen: 1 year

Day(s) Performed

Sun-Sat

Performing Lab - Department

TUKHS-BH-Mail Outs

CPT Code

83993

LOINC Code

38445-3

Test Alias

Fecal Calprotectin
Stool Calprotectin

Additional Information / Notes

Fecal Calprotectin is an indicator of the presence of neutrophils in stool and is not specific for IBD. Other intestinal ailments including GI infections and colorectal cancer can result in elevated concentrations of calprotectin. The diagnosis of IBD cannot be established solely on the basis of a positive calprotectin result. Patients with IBD fluctuate between active and inactive stages of disease. Calprotectin results may also fluctuate. GI bleeding of as much as 100 mL per day will increase the fecal calprotectin concentration by only 15 µg/g.