Sign in →

Test Code GISTP GIST 3 Gene NGS Panel (KIT, PDGFRA, BRAF)

Clinical Indications

N/A

Additional Test Codes

Epic Order Name: GIST PANEL 3 GENES
Sunquest Order Code: GISTP
Epic Px Code: LAB8200

Specimen Collection Type

FFPE tissue: 5 to 10 slides, each up to 10 ?m thick plus one additional H&E reference slide with tumor tissue marked.

Minimum Collection Volume

FFPE: 5 unstained slides + 1 representative H&E

Additional Information / Notes

Detects somatic small nucleotide variations (SNVs) and small insertions/deletions (INDELs) in KIT, PDGFRA, and BRAF. Variants in these genes are common in gastrointestinal stromal tumors (GISTs), and may serve as a prognostic indicator and determine response to some tyrosine kinase inhibitor (TKI) therapies.

Reference Range

An interpretive report will be provided

Critical Value

N/A

Interpretation

An interpretive report will be provided

Rejection Criteria

FFPE tumor specimen with a tumor percentage < 5 %, or with otherwise inadequate cellular content.

Specimen Availability for Add-on Testing

Only for additional CMOL testing; additional sample may be required, see test sample requirements and stability.

Specimen Stability

FFPE: n/a.

Day(s) Performed

9:00 AM – 5:00 PM, Monday through Friday; varies

Performing Lab - Department

Clinical Molecular Oncology Laboratory

CPT Code

BRAF (81210), KIT (81272, 81273), PDGFRA (81314)

LOINC Code

N/A

Test Alias

N/A