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Test Code GLNGS Glioma NGS Panel (BRAF, IDH1, IDH2)

Clinical Indications

N/A

Additional Test Codes

Epic Order Name: GLIOMA NGS PANEL
Sunquest Order Code: GLNGS
Epic Px Code: LAB8196

Specimen Collection Type

FFPE tissue: 5 to 10 slides, each up to 10 ?m thick plus one additional H&E reference slide with tumor tissue marked.

Minimum Collection Volume

FFPE: 5 unstained slides + 1 representative H&E

Additional Information / Notes

Detects somatic small nucleotide variations (SNVs) and small insertions/deletions (INDELs) in BRAF, IDH1 and IDH2. This targeted next-generation sequencing panel is designed to detect somatic small nucleotide variations (SNVs) and small insertions/deletions (INDELs) in BRAF, IDH1, and IDH2. The detection of variants present in these genes can serve as a prognostic indicator and assist in guiding treatment decisions for gliomas.

Reference Range

An interpretive report will be provided

Critical Value

N/A

Interpretation

An interpretive report will be provided

Rejection Criteria

FFPE tumor specimen with a tumor percentage < 5 %, or with otherwise inadequate cellular content.

Specimen Availability for Add-on Testing

Only for additional CMOL testing; additional sample may be required, see test sample requirements and stability.

Specimen Stability

FFPE: n/a.

Day(s) Performed

9:00 AM – 5:00 PM, Monday through Friday; varies

Performing Lab - Department

Clinical Molecular Oncology Laboratory

CPT Code

BRAF (81210), IDH1 (81120), IDH2 (81121)

LOINC Code

N/A

Test Alias

N/A