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Test Code HHV6P HHV-6 Quantitative Real-time PCR (Plasma)

Clinical Indications

Quantitative HHV-6 DNA PCR can be used for
early detection of a primary infection, for tracking the course of
infection, and for monitoring response to treatment. Quantitative
HHV-6 DNA
PCR does not differentiate HHV-6 viremia from patients with chromosomally
integrated HHV-6, a relatively uncommon
congenital occurrence that has not been conclusively related to a
disease state. Treatment of HHV-6 in
immunocompromised patients presents challenges, including drug
toxicity, delayed onset of disease after discontinuing therapy, and
emergence of mutations that may affect the ability of diagnostic
assays to detect them efficiently.

Additional Test Codes

Epic Order Name: HUMAN HERPES VIRUS 6 PCR PLASMA (aka HHV6P)
Sunquest Order Code: HHV6P
Epic Px Code: LAB2861

Specimen Collection Type

Preferred: Lavender (EDTA)
Acceptable: Yellow (ACD solution)

Minimum Collection Volume

0.5 mL

Reference Range

188 copies/mL to 1×10^8 copies/mL

Critical Value

N/A

Interpretation

Detects both Type A and Type B in one assay. The primers and
probes used in this assay are specific for known strains of
HHV-6 based on similarity search
algorithms. Additionally, no cross reactivity was detected when
tested against adenoviruses, BKV,
CMV, EBV,
HSV-1, HSV-2,
HHV-7, HHV-8,
JCV, parvovirus B19, SV-40, and
VZV.

Rejection Criteria

Specimens beyond their acceptable length of time from collection
as listed in the specimen stability

Specimen Availability for Add-on Testing

1 Day

Specimen Stability

Ambient (preferred): 4 days
Refrigerated: 4 days
Frozen: 7 days

Day(s) Performed

Monday through Saturday

Performing Lab- Department

TUKHS-BH-Mail Outs

CPT Code

87533

LOINC Code

N/A

Test Alias

Herpes Virus-6 PCR, Plasma
Herpesvirus 6 PCR, Plasma
HHV-6 DNA
Quant, Plasma

Human Herpes Virus-6 PCR, Plasma

Additional Information / Notes

Turnaround time: Same day (within 8 – 12 hours from
receipt of specimen)