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Test Code HNB141 Hematologic Neoplasms Targete Gene NGS Panel (141) - Non Blood

Clinical Indications

N/A

Additional Test Codes

Epic Order Name: HEMATOLOGIC NEOPLASMS GENE PANEL NGS NONBLOOD
Sunquest Order Code: HNB141
Epic Px Code: LAB8211

Specimen Collection Type

Bone Marrow Aspirate: EDTA (lavender-top) tube, 3.0 mL (Minimum 0.5 mL);
FFPE tissue: 5 to 10 slides, each up to 10 ?m thick plus one additional H&E reference slide with tumor tissue marked.

Minimum Collection Volume

Bone Marrow Aspirate: 0.5 ml;
FFPE: 5 unstained slides + 1 representative H&E

Additional Information / Notes

Detects somatic small nucleotide variations (SNVs) and small insertions/deletions (INDELs) in 141 genes of importance across various types of hematologic malignancies. Useful for diagnosis support, prognosis, risk stratification, and informing possible treatment decisions and clinical trials. The presence of gene variants in various cancers can serve as a prognostic indicator and can impact a patient’s response to some anti-cancer therapies, making detection of gene variants useful in guiding treatment decisions.

Reference Range

An interpretive report will be provided

Critical Value

N/A

Interpretation

An interpretive report will be provided

Rejection Criteria

Frozen, severely hemolyzed, or clotten specimen. FFPE tumor specimen with a tumor percentage < 5 %, or with otherwise inadequate cellular content.

Specimen Availability for Add-on Testing

Only for additional CMOL testing; additional sample may be required, see test sample requirements and stability.

Specimen Stability

Blood/Bone Marrow Aspirate: 96 hrs at 4°C;
FFPE: n/a.

Day(s) Performed

9:00 AM – 5:00 PM, Monday through Friday; varies

Performing Lab - Department

Clinical Molecular Oncology Laboratory

CPT Code

81455

LOINC Code

N/A

Test Alias

N/A