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Test Code JAK2RB JAK2 V617F, with reflex to JAK2 exon 12, CALR, MPL - Real-time PCR, Blood

Clinical Indications

N/A

Additional Test Codes

Epic Order Name: JAK2 BLOOD V617F VARIANT REFLEX
Sunquest Order Code: JAK2RB
Epic Px Code: LAB3054

Specimen Collection Type

Blood: EDTA (lavender-top) tube, 3.0 mL (Minimum 0.5 mL).

Minimum Collection Volume

Blood: 0.5 ml

Additional Information / Notes

Useful for the diagnosis of and discrimination between Ph-negative myeloproliferative neoplasms (MPNs). Detects the JAK2 V617F variant in exon 14; if negative, testing reflexes to JAK2 NGS (exons 3-25), then to CALR, then MPL.

Reference Range

An interpretive report will be provided

Critical Value

N/A

Interpretation

An interpretive report will be provided

Rejection Criteria

Frozen, severely hemolyzed, or clotten specimen.

Specimen Availability for Add-on Testing

Only for additional CMOL testing; additional sample may be required, see test sample requirements and stability.

Specimen Stability

Blood: 96 hrs at 4°C.

Day(s) Performed

9:00 AM – 5:00 PM, Monday through Friday; varies

Performing Lab - Department

Clinical Molecular Oncology Laboratory

CPT Code

81270

LOINC Code

N/A

Test Alias

N/A