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Test Code JAK2RM JAK2 V617F and exon 12, with reflex to CALR, MPL - Next-Generation Sequencing, Bone Marrow

Clinical Indications

N/A

Additional Test Codes

Epic Order Name: JAK2 NGS EXONS 3-25 BONE MARROW REFLEX
Sunquest Order Code: JAK2RM
Epic Px Code: LAB1023

Specimen Collection Type

Bone Marrow Aspirate: EDTA (lavender-top) tube, 3.0 mL (Minimum 0.5 mL).

Minimum Collection Volume

Bone Marrow Aspirate: 0.5 ml

Additional Information / Notes

Useful for the diagnosis of and discrimination between Ph-negative myeloproliferative neoplasms (MPNs). Detects JAK2 exon 14 V617F variant as well as exon 12 variants. If negative for JAK2 variants testing reflexes to CALR then MPL.

Reference Range

An interpretive report will be provided

Critical Value

N/A

Interpretation

An interpretive report will be provided

Rejection Criteria

Frozen, severely hemolyzed, or clotten specimen.

Specimen Availability for Add-on Testing

Only for additional CMOL testing; additional sample may be required, see test sample requirements and stability.

Specimen Stability

Bone Marrow Aspirate: 96 hrs at 4°C.

Day(s) Performed

9:00 AM – 5:00 PM, Monday through Friday; varies

Performing Lab - Department

Clinical Molecular Oncology Laboratory

CPT Code

81403

LOINC Code

N/A

Test Alias

N/A