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Test Code KMANB KIT - Next-Generation Sequencing, Non Blood

Clinical Indications

N/A

Additional Test Codes

Epic Order Name: KIT MUT D816V EXONS 8 & 17 NON-BLOOD
Sunquest Order Code: KMANB
Epic Px Code: LAB8206

Specimen Collection Type

Bone Marrow Aspirate: EDTA (lavender-top) tube, 3.0 mL (Minimum 0.5 mL);
FFPE tissue: 5 to 10 slides, each up to 10 ?m thick plus one additional H&E reference slide with tumor tissue marked.

Minimum Collection Volume

Bone Marrow Aspirate: 0.5 ml;
FFPE: 5 unstained slides + 1 representative H&E

Additional Information / Notes

Useful for diagnosis and TKI treatment prediction for mastocytosis and acute myeloid leukemia. Useful for predicting response to TKIs in gastrointestinal stromal tumors (GISTs) and melanomas.

Reference Range

An interpretive report will be provided

Critical Value

N/A

Interpretation

An interpretive report will be provided

Rejection Criteria

Frozen, severely hemolyzed, or clotten specimen. FFPE tumor specimen with a tumor percentage < 5 %, or with otherwise inadequate cellular content.

Specimen Availability for Add-on Testing

Only for additional CMOL testing; additional sample may be required, see test sample requirements and stability.

Specimen Stability

Bone Marrow Aspirate: 96 hrs at 4°C;
FFPE: n/a.

Day(s) Performed

9:00 AM – 5:00 PM, Monday through Friday; varies

Performing Lab - Department

Clinical Molecular Oncology Laboratory

CPT Code

81272, 81273

LOINC Code

N/A

Test Alias

N/A