FFPE tissue: 5 to 10 slides, each up to 10 ?m thick plus one additional H&E reference slide with both tumor tissue and normal tissue (no tumor) clearly marked.

Minimum Collection Volume

FFPE: 5 unstained slides + 1 representative H&E; Normal and tumor tissue must both be present and clearly differentiated.

Additional Information / Notes

Useful for identify patients at risk for Lynch syndrome. This test compares representative normal and tumor tissue at five microsatellite regions. A clearly marked “normal” (tumor-free) sample is required for analysis. Samples without a corresponding “normal” sample cannot be adequately analyzed and will be rejected.

Reference Range

An interpretive report will be provided

Critical Value

N/A

Interpretation

An interpretive report will be provided

Rejection Criteria

FFPE tumor specimen with a tumor percentage < 5 %, or with otherwise inadequate cellular content. Specimen with no corresponding “normal” (tumor-free) tissue.

Specimen Availability for Add-on Testing

Only for additional CMOL testing; additional sample may be required, see test sample requirements and stability.

Specimen Stability

FFPE: n/a.

Day(s) Performed

9:00 AM – 5:00 PM, Monday through Friday; varies

Performing Lab - Department

Clinical Molecular Oncology Laboratory

CPT Code

81301

LOINC Code

N/A

Test Alias

N/A

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Test Code MSIPCR Microsatellite Instability (MSI), PCR

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