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Test Code NONGS Neuro-Oncology NGS Panel (IDH1, IDH2, BRAF, EGFR, PTEN)

Clinical Indications

N/A

Additional Test Codes

Epic Order Name: NEURO ONCOLOGY NGS PANEL
Sunquest Order Code: NONGS
Epic Px Code: LAB8195

Specimen Collection Type

FFPE tissue: 5 to 10 slides, each up to 10 ?m thick plus one additional H&E reference slide with tumor tissue marked.

Minimum Collection Volume

FFPE: 5 unstained slides + 1 representative H&E

Additional Information / Notes

Detects somatic small nucleotide variations (SNVs) and small insertions/deletions (INDELs) in IDH1, IDH2, BRAF, EGFR and PTEN. Detection of somatic variants in these genes is useful for prognosis and guiding therapeutic management for central nervous system tumors.

Reference Range

An interpretive report will be provided

Critical Value

N/A

Interpretation

An interpretive report will be provided

Rejection Criteria

FFPE tumor specimen with a tumor percentage < 5 %, or with otherwise inadequate cellular content.

Specimen Availability for Add-on Testing

Only for additional CMOL testing; additional sample may be required, see test sample requirements and stability.

Specimen Stability

FFPE: n/a.

Day(s) Performed

9:00 AM – 5:00 PM, Monday through Friday; varies

Performing Lab - Department

Clinical Molecular Oncology Laboratory

CPT Code

81445

LOINC Code

N/A

Test Alias

N/A