Test Code NONGS Neuro-Oncology NGS Panel (IDH1, IDH2, BRAF, EGFR, PTEN)
Clinical Indications
N/A
Additional Test Codes
Epic Order Name: NEURO ONCOLOGY NGS PANEL
Sunquest Order Code: NONGS
Epic Px Code: LAB8195
Specimen Collection Type
FFPE tissue: 5 to 10 slides, each up to 10 ?m thick plus one additional H&E reference slide with tumor tissue marked.
Minimum Collection Volume
FFPE: 5 unstained slides + 1 representative H&E
Additional Information / Notes
Detects somatic small nucleotide variations (SNVs) and small insertions/deletions (INDELs) in IDH1, IDH2, BRAF, EGFR and PTEN. Detection of somatic variants in these genes is useful for prognosis and guiding therapeutic management for central nervous system tumors.
Reference Range
An interpretive report will be provided
Critical Value
N/A
Interpretation
An interpretive report will be provided
Rejection Criteria
FFPE tumor specimen with a tumor percentage < 5 %, or with otherwise inadequate cellular content.
Specimen Availability for Add-on Testing
Only for additional CMOL testing; additional sample may be required, see test sample requirements and stability.
Specimen Stability
FFPE: n/a.
Day(s) Performed
9:00 AM – 5:00 PM, Monday through Friday; varies
Performing Lab - Department
Clinical Molecular Oncology Laboratory
CPT Code
81445
LOINC Code
N/A
Test Alias
N/A