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Test Code PTRIP Protriptyline, Serum or Plasma

Clinical Indications

Optimize drug therapy and monitor patient adherence.

Additional Test Codes

Epic Order Name: PROTRIPTYLENE LEVEL (aka PTRIP)
Sunquest Order Code: PTRIP
Epic Px Code: LAB2449

Specimen Collection Type

Preferred: Red
Acceptable: Lavender (EDTA)

Minimum Collection Volume

0.5 mL

Reference Range

Therapeutic Range:
70-240 ng/mL
Toxic: > 400 ng/mL

Critical Value

> 400 ng/mL

Interpretation

Toxic concentrations may cause hypotension, cardiac abnormalities, seizures and coma.

Rejection Criteria

Whole blood. Gel separator tubes, light blue (citrate), dark green (sodium heparin), or yellow (SPS or ACD solution).

Specimen Availability for Add-on Testing

2 Days

Specimen Stability

Refrigerated (preferred): 5 days
Ambient: 5 days
Frozen: 6 months

Day(s) Performed

Mon, Wed, Fri

Performing Lab- Department

TUKHS-BH-Mail Outs

CPT Code

80335

LOINC Code

3999-0

Test Alias

protriptyline blood level
Triptil
Vivactil
vivactil blood level

Additional Information / Notes

Timing of specimen collection: Pre-dose (trough) draw – At steady state concentration.