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Test Code PVIGM Parvovirus B 19 Antibody, IgM

Clinical Indications

Not recommended as a stand-alone test. Parvovirus B19 Antibodies, IgG and IgM is preferred.

Additional Test Codes

Epic Order Name:
Sunquest Order Code: PVIGM
Epic Px Code: LAB

Specimen Collection Type

Gold-top serum (preferred)
Red-top serum
Lavender-top EDTA plasma
Green-top (sodium or lithium heparin) plasma

Minimum Collection Volume

0.75 mL

Reference Range

0.89 IV or less: Negative – No significant level of detectable Parvovirus B19 IgM antibody.
0.90-1.10 IV: Equivocal – Repeat testing in 10-14 days may be helpful.
1.11 IV or greater: Positive – IgM antibody to Parvovirus B19 detected, which may indicate a current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.

Critical Value

N/A

Interpretation

The best evidence for current infection is a significant change on two appropriately timed specimens, where both tests are done in the same laboratory at the same time.

Appearance of an IgM antibody response normally occurs 7 to 14 days after the onset of disease. Testing immediately post-exposure is of no value without a later convalescent specimen. A residual IgM response may be distinguished from early IgM response to infection by testing sera from patients three to four weeks later for changing levels of specific IgM antibodies.

Rejection Criteria

Contaminated, heat-inactivated, hemolyzed, hyperlipemic, or icteric specimens

Specimen Availability for Add-on Testing

2 days

Specimen Stability

Refrigerated (preferred): 2 weeks
Ambient: 48 hours
Frozen: 1 year

Day(s) Performed

Sun-Sat

Performing Lab - Department

TUKHS-BH-Mail Outs

CPT Code

86747

LOINC Code

5274-6

Test Alias

B19 IgM Antibodies
Erythrovirus B19 IgM
Human Parvovirus B19 IgM

Additional Information / Notes

Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as “acute” or “convalescent.”