Test Code VZVSS Varicella Zoster Virus (VZV) Qualitative Real-time PCR (Skin swab)
Clinical Indications
VZV
reactivation is commonly seen in
immunocompromised individuals. These patients are more likely
to
have disseminated disease with extensive skin lesions,
pneumonia,
hepatitis, or encephalitis. Proper management is dependent upon
early diagnosis; quantitative DNA
PCR is a rapid
and sensitive tool useful
for detecting the virus, tracking the course of the infection,
and
monitoring response to treatment.
Additional Test Codes
Epic Order Name: VZV PCR QUAL, SKIN
Sunquest Order Code: VZVSS
Epic Px Code: LAB2956
Specimen Collection Type
Sterile swab of site placed in viral transport media (M4-RT,
M4,
or M5 media). Do not use calcium alginate swab or wood shafted
swab.
Minimum Collection Volume
N/A
Reference Range
Detected/Not Detected
Critical Value
N/A
Interpretation
The primers and probes used in this assay are specific for
VZV based on
similarity search
algorithms. Additionally, no cross reactivity was detected when
tested against adenoviruses, BKV,
CMV,
EBV,
HSV-1,
HSV-2,
HHV-6 variant
A, HHV-6
variant B, HHV-7,
HHV-8,
JCV,
parvovirus B19, and SV-40.
Rejection Criteria
Specimens beyond their acceptable length of time from
collection
as listed in the specimen stability, specimens other than those
listed. Do not use calcium alginate swab or wood shafted swab.
Specimen Availability for Add-on Testing
This test cannot be added on.
Specimen Stability
Refrigerated (preferred): 4 days
Frozen: 7 days
Ambient: 1 day
Day(s) Performed
Monday through Saturday
Performing Lab- Department
TUKHS-BH-Mail Outs
CPT Code
87798
LOINC Code
N/A
Test Alias
Herpes Zoster, Skin swab
VZV molecular
detection, Skin swab
VZV
PCR, Skin
swab
Additional Information / Notes
Turnaround time: Same day (within 8 – 12 hours from
receipt of specimen)
Note: This is a qualitative assay